Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sox2  SRY (sex determining region Y)-box 2   (Synonyms: lcc, Sox-2, ysb)
Results	Reference
1	J:327432 Chen T, Alcorn H, Devbhandari S, Remus D, Lacy E, Huangfu D, Anderson KV, A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation. Biol Open. 2022 Aug 15;11(8):bio059307
1	J:137623 Foshay KM, Gallicano GI, Regulation of Sox2 by STAT3 initiates commitment to the neural precursor cell fate. Stem Cells Dev. 2008 Apr;17(2):269-78
1	J:189004 Iwafuchi-Doi M, Matsuda K, Murakami K, Niwa H, Tesar PJ, Aruga J, Matsuo I, Kondoh H, Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells. Development. 2012 Nov;139(21):3926-37
1*	J:274134 Javali A, Misra A, Leonavicius K, Acharyya D, Vyas B, Sambasivan R, Co-expression of Tbx6 and Sox2 identifies a novel transient neuromesoderm progenitor cell state. Development. 2017 Dec 15;144(24):4522-4529
1*	J:148612 Jin Z, Liu L, Bian W, Chen Y, Xu G, Cheng L, Jing N, Different transcription factors regulate nestin gene expression during P19 cell neural differentiation and central nervous system development. J Biol Chem. 2009 Mar 20;284(12):8160-73
1	J:244157 Lange L, Marks M, Liu J, Wittler L, Bauer H, Piehl S, Blass G, Timmermann B, Herrmann BG, Patterning and gastrulation defects caused by the tw18 lethal are due to loss of Ppp2r1a. Biol Open. 2017 Jun 15;6(6):752-764
1	J:239071 Li X, Yue X, Pastor WA, Lin L, Georges R, Chavez L, Evans SM, Rao A, Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):E8267-E8276
1	J:308524 Morgani SM, Hadjantonakis AK, Quantitative analysis of signaling responses during mouse primordial germ cell specification. Biol Open. 2021 May 15;10(5):bio058741
1	J:258132 Morgani SM, Metzger JJ, Nichols J, Siggia ED, Hadjantonakis AK, Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning. Elife. 2018 Feb 7;7:e32839
1	J:308051 Morgani SM, Su J, Nichols J, Massague J, Hadjantonakis AK, The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos. Elife. 2021 Apr 30;10:e64811
1	J:238551 Ramkumar N, Omelchenko T, Silva-Gagliardi NF, McGlade CJ, Wijnholds J, Anderson KV, Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation. Nat Cell Biol. 2016 Dec;18(12):1281-1291
1	J:275024 Senft AD, Bikoff EK, Robertson EJ, Costello I, Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse. Nat Commun. 2019 Mar 6;10(1):1089
1	J:341534 Thawani A, Maunsell HR, Zhang H, Ankamreddy H, Groves AK, The Foxi3 transcription factor is necessary for the fate restriction of placodal lineages at the neural plate border. Development. 2023 Oct 1;150(19):dev202047
1*	J:290529 Wallingford MC, Hiller J, Zhang K, Mager J, YY1 Is Required for Posttranscriptional Stability of SOX2 and OCT4 Proteins. Cell Reprogram. 2017 Aug;19(4):263-269
1	J:159214 Wong YH, Lu AC, Wang YC, Cheng HC, Chang C, Chen PH, Yu JY, Fann MJ, Protogenin defines a transition stage during embryonic neurogenesis and prevents precocious neuronal differentiation. J Neurosci. 2010 Mar 24;30(12):4428-39
1	J:229981 Wymeersch FJ, Huang Y, Blin G, Cambray N, Wilkie R, Wong FC, Wilson V, Position-dependent plasticity of distinct progenitor types in the primitive streak. Elife. 2016;5:e10042
1	J:340447 Zhai J, Guo J, Wan H, Qi L, Liu L, Xiao Z, Yan L, Schmitz DA, Xu Y, Yu D, Wu X, Zhao W, Yu K, Jiang X, Guo F, Wu J, Wang H, Primate gastrulation and early organogenesis at single-cell resolution. Nature. 2022 Dec;612(7941):732-738